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Article

Study of Association between Pre-Senile Cataracts and the Polymorphisms rs2228000 in XPC and rs1042522 in p53 in Spanish Population.

PloS one - 1 Jan 2016

López Valverde Gloria, Garcia Martin Elena, Larrosa Povés José M, Polo Llorens Vicente, Fernández Mateos Javier, Pablo Júlvez Luis E, González Sarmiento Rogelio

Abstract excerpt

PURPOSE: To determine if the presence of certain polymorphisms in the DNA repair gene XPC and the apoptosis inductor gene p53 is associated with pre-senile cataract development. METHODS: We have performed a retrospective study over three groups of patients. The group with pre-senile cataract formed by 72 patients younger than 55 with cataract surgery. The group with senile cataract formed by 101 patients older...

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Identifiers

PMID: 27248495
DOI: 10.1371/journal.pone.0156317
PMCID: PMC4889128

Genes

XPC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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