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Article

MC1R variants affect the expression of melanocortin and melanogenic genes and the association between melanocortin genes and coloration.

Molecular ecology - 1 Jan 2017

San-Jose Luis M, Ducrest Anne-Lyse, Ducret Valérie, Simon Céline, Richter Hannes, Wakamatsu Kazumasa, Roulin Alexandre

Abstract excerpt

The melanocortin-1 receptor (MC1R) gene influences coloration by altering the expression of genes acting downstream in the melanin synthesis. MC1R belongs to the melanocortin system, a genetic network coding for the ligands that regulate MC1R and other melanocortin receptors controlling different physiological and behavioural traits. The impact of MC1R variants on these regulatory melanocortin genes was never...

Topics

Alleles
Animals
Feathers
Gene Regulatory Networks
Genotype
Melanocortins
Pigmentation
Receptor, Melanocortin, Type 1
Strigiformes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27664794
DOI: 10.1111/mec.13861

Genes

ASIP
DCT
KIT
OCA2
PCSK2
TYR
TYRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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