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Article

Positive Selection Drives Rapid Evolution of the meq Oncogene of Marek’s Disease Virus

23 Sept 2016

Abstract excerpt

Marek's disease (MD), caused by Marek's disease virus (MDV), a poultry-borne alphaherpesvirus, is a devastating disease of poultry causing an estimated annual loss of one billion dollars to poultry producers, worldwide. Despite decades of control through vaccination, MDV field strains continue to emerge having increased virulence. The evolutionary mechanism driving the emergence of this continuum of strains to...

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PMID: 27662574
DOI: 10.1371/journal.pone.0162180

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