Article
Genetic characterization of a Marek's disease virus strain isolated in Japan.
Virology journal - 23 Nov 2020
Murata Shiro, Machida Yuka, Isezaki Masayoshi, Maekawa Naoya, Okagawa Tomohiro, Konnai Satoru, Ohashi Kazuhiko
Abstract excerpt
BACKGROUND: Marek's disease virus (MDV) causes malignant lymphomas in chickens (Marek's disease, MD). MD is currently controlled by vaccination; however, MDV strains have a tendency to develop increased virulence. Distinct diversity and point mutations are present in the Meq proteins, the oncoproteins of MDV, suggesting that changes in protein function induced by amino acid substitutions might affect MDV...
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