Article
Familial Risk of Biliary Tract Cancers: A Population-Based Study in Utah.
Digestive diseases and sciences - 1 Dec 2016
Samadder N Jewel, Smith Ken Robert, Wong Jathine, Hanson Heidi, Boucher Kenneth, Burt Randall W, Charlton Michael, Byrne Kathryn R, Gallegos-Orozco Juan F, Koptiuch Cathryn, Curtin Karen
Abstract excerpt
BACKGROUND AND OBJECTIVES: Biliary tract cancers (BTC) including, cholangiocarcinoma (CC) and gallbladder cancer (GBC), are rare and highly fatal malignancies. The etiology and inherited susceptibility of both malignancies are poorly understood. We quantified the risk of BTC in first-degree (FDR), second-degree (SDR), and first cousin (FC) relatives of individuals with BTC, stratified by tumor subsite. METHODS:...
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