Article
Association of CYP2C19 Polymorphisms with the Clinical Efficacy of Clopidogrel Therapy in Patients Undergoing Carotid Artery Stenting in Asia.
Scientific reports - 3 May 2016
Zhu Wen-Yao, Zhao Ting, Xiong Xiao-Yi, Li Jie, Wang Li, Zhou Yu, Gong Zi-Li, Cheng Sai-Yu, Liu Yong, Shuai Jie, Yang Qing-Wu
Abstract excerpt
The CYP2C19 gene plays a detrimental role in the metabolism of clopidogrel. This study aimed to investigate the association between CYP2C19 polymorphisms and the clinical efficacy of clopidogrel therapy in patients who have undergone carotid artery stenting (CAS). CYP2C19 genotype screening was performed on 959 ischemic stroke patients. Of these patients, 241 who had undergone CAS were enrolled in the study. They...
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