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Pathogenicity Comparison Between the Kikwit and Makona Ebola Virus Variants in Rhesus Macaques

19 Sept 2016

Abstract excerpt

Enhanced virulence and/or transmission of West African Ebola virus (EBOV) variants, which are divergent from their Central African counterparts, are suspected to have contributed to the sizable toll of the recent Ebola virus disease (EVD) outbreak. This study evaluated the pathogenicity and shedding in rhesus macaques infected with 1 of 2 West African isolates (EBOV-C05 or EBOV-C07) or a Central African isolate...

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PMID: 27651412
DOI: 10.1093/infdis/jiw267

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