Article
Morphological and smooth muscle cell phenotypic changes in fetal rabbit aorta during early development.
Basic research in cardiology - 1 Jan 2000
Cayatte A J, Ashraf M, Subbiah M T
Abstract excerpt
Previous studies from our laboratory noted a) high aortic cholesterol esterification activity in the fetal rabbit, and b) increased susceptibility of fetal aortic explants to smooth muscle cell proliferation in culture, two features commonly associated with atherogenesis. This prompted us to examine in detail morphological development of fetal aorta and its relationship to fetal plasma cholesterol levels. Our...
Topics
- Animals
- Animals, Newborn
- Aorta
- Arteriosclerosis
- Cholesterol
- Elastic Tissue
- Endothelium, Vascular
- Female
- Microscopy, Electron, Scanning
- Muscle, Smooth, Vascular
- Phenotype