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Article

Potential synergistic action of 19 schizophrenia risk genes in the thalamus.

Schizophrenia research - 1 Feb 2017

Richard Edwin A, Khlestova Elizaveta, Nanu Roshan, Lisman John E

Abstract excerpt

A goal of current schizophrenia (SZ) research is to understand how multiple risk genes work together with environmental factors to produce the disease. In schizophrenia, there is elevated delta frequency EEG power in the awake state, an elevation that can be mimicked in rodents by N-methyl-d-aspartate receptor (NMDAR) antagonist action in the thalamus. This thalamic delta can be blocked by dopamine D2 receptor...

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Identifiers

PMID: 27645107
DOI: 10.1016/j.schres.2016.09.008
PMCID: PMC5263182

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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