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Article

Reliable Next-Generation Sequencing of Formalin-Fixed, Paraffin-Embedded Tissue Using Single Molecule Tags.

The Journal of molecular diagnostics : JMD - 1 Nov 2016

Eijkelenboom Astrid, Kamping Eveline J, Kastner-van Raaij Annemiek W, Hendriks-Cornelissen Sandra J, Neveling Kornelia, Kuiper Roland P, Hoischen Alexander, Nelen Marcel R, Ligtenberg Marjolijn J L, Tops Bastiaan B J

Abstract excerpt

Sequencing of tumor DNA to detect genetic aberrations is becoming increasingly important, not only to refine cancer diagnoses but also to predict response to targeted treatments. Next-generation sequencing is widely adopted in diagnostics for the analyses of DNA extracted from routinely processed formalin-fixed, paraffin-embedded tissue, fine-needle aspirates, or cytologic smears. PCR-based enrichment strategies...

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PMID: 27637301
DOI: 10.1016/j.jmoldx.2016.06.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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