Article
Dopamine receptor DOP-4 modulates habituation to repetitive photoactivation of a C. elegans polymodal nociceptor.
Learning & memory (Cold Spring Harbor, N.Y.) - 1 Oct 2016
Ardiel Evan L, Giles Andrew C, Yu Alex J, Lindsay Theodore H, Lockery Shawn R, Rankin Catharine H
Abstract excerpt
Habituation is a highly conserved phenomenon that remains poorly understood at the molecular level. Invertebrate model systems, like Caenorhabditis elegans, can be a powerful tool for investigating this fundamental process. Here we established a high-throughput learning assay that used real-time computer vision software for behavioral tracking and optogenetics for stimulation of the C. elegans polymodal...
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