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Article

miR-378 inhibits cell growth and enhances apoptosis in human myelodysplastic syndromes

13 Sept 2016

Abstract excerpt

miR-378 has been proven to inhibit cell growth, migration and invasion in different types of cancers. In this study, we found that miR-378 was commonly downregulated in the bone marrow cells obtained from myelodysplastic syndrome (MDS) patients. We further investigated the role of miR-378 in the proliferation and apoptosis of SKM-1 cells, an acute myeloid leukemia cell line established in the leukemic phase...

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Identifiers

PMID: 27633496
DOI: 10.3892/ijo.2016.3689

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