Article
Low frequency of V617F mutation in JAK2 gene in Indian patients with hepatic venous outflow obstruction and extrahepatic portal venous obstruction.
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology - 1 Sept 2016
Rai Praveer, Kumar Pankaj, Mishra Swapnil, Aggarwal Rakesh
Abstract excerpt
BACKGROUND: Hepatic venous outflow tract obstruction (HVOTO) and extrahepatic portal venous obstruction (EHPVO) are important causes of portal hypertension and related complications in India. Both these conditions result from splanchnic venous thrombosis. In recent years, a V617F somatic mutation in Janus kinase 2 (JAK2) gene which is highly specific for myeloproliferative disorders has been detected in 40 % to...
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