Article
The JAK2 V617F mutation frequently occurs in patients with portal and mesenteric venous thrombosis.
Journal of thrombosis and haemostasis : JTH - 1 Jan 2007
Colaizzo D, Amitrano L, Tiscia G L, Scenna G, Grandone E, Guardascione M A, Brancaccio V, Margaglione M
Abstract excerpt
BACKGROUND: Myeloproliferative disorders (MPDs) represent a risk factor for thrombosis in the portal, mesenteric, and hepatic districts. OBJECTIVE: We aimed to assess whether the Janus kinase 2 (JAK2) V617F mutation, an acquired mutation that occurs in MPD patients, is a risk factor for portal and mesenteric venous thrombosis (PMVT) independently of the presence of overt MPDs. PATIENTS AND METHODS: The medical...
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