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Integrated proteomic and transcriptomic landscape of human placenta in small for gestational age infants

19 Nov 2024

Abstract excerpt

Small for gestational age (SGA) infants affected by placental insufficiency are exposed to the risk of stillbirth and long-term complications. Based on RNA-seq and mass spectrometry, we identified dysregulated RNAs and proteins from the comparisons of SGA placental tissues and controls. We revealed two SGA-relevant co-expression modules (SRMs) that also significantly distinguished SGA from controls. Then we...

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PMID: 39687015
DOI: 10.1016/j.isci.2024.111423

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