Article
Strong KDM4B and KDM4D Expression Associates with Radioresistance and Aggressive Phenotype in Classical Hodgkin Lymphoma.
Anticancer research - 1 Sept 2016
Bur Hamid, Haapasaari Kirsi-Maria, Turpeenniemi-Hujanen Taina, Kuittinen Outi, Auvinen Päivi, Marin Katja, Soini Ylermi, Karihtala Peeter
Abstract excerpt
BACKGROUND: Epigenetic regulators, including Jumonji domain 2 (JMJD2/KDM4) proteins are involved in post-translational modification of histone demethylation and have a major role in carcinogenesis of many solid tumors. MATERIALS AND METHODS: We assessed immunohistochemically the expression of lysine (K)-specific demethylase 4 (KDM4)A, KDM4B and KDM4D in tumors from 91 patients of adriamycin, bleomycin,...
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