Article
Technical Advance: Changes in neutrophil migration patterns upon contact with platelets in a microfluidic assay.
Journal of leukocyte biology - 1 Mar 2017
Frydman Galit H, Le Anna, Ellett Felix, Jorgensen Julianne, Fox James G, Tompkins Ronald G, Irimia Daniel
Abstract excerpt
Neutrophils are traditionally regarded as the "first responders" of the immune system. However, recent observations revealed that platelets often respond earlier to recruit and activate neutrophils within sites of injury and inflammation. Currently, platelet-neutrophil interactions are studied by intravital microscopy. Although such studies provide exceptional, physiologic in vivo data, they are also laborious...
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