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Article

Metabolic Signatures of Genetically Elevated Vitamin D Among Chinese: Observational and Mendelian Randomization Study.

The Journal of clinical endocrinology and metabolism - 13 Jul 2021

Zhuang Zhenhuang, Yu Canqing, Guo Yu, Bian Zheng, Yang Ling, Millwood Iona Y, Walters Robin G, Chen Yiping, Xu Qinai, Zou Mingyuan, Chen Junshi, Chen Zhengming, Lv Jun, Huang Tao, Li Liming

Abstract excerpt

CONTEXT: Observational studies have suggested that higher circulating 25-hydroxyvitamin D [25(OH)D] levels are associated with favorable serum lipids and related metabolites. However, whether such observations reflect causality remains unclear. OBJECTIVE: We aimed to investigate the causal effect of elevated 25(OH)D with a detailed systemic metabolite profile in Chinese adults. METHODS: A total of 225 lipid and...

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Identifiers

PMID: 33596318
DOI: 10.1210/clinem/dgab097
PMCID: PMC7612493

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