Article
Association of serum 25-hydroxyvitamin D concentration with HLA-B, -DRB1 and -DQB1 genetic polymorphisms.
European journal of clinical nutrition - 1 Jan 2017
Miettinen M E, Kinnunen L, Harjutsalo V, Aimonen K, Surcel H-M, Lamberg-Allardt C, Tuomilehto J
Abstract excerpt
BACKGROUND/OBJECTIVES: The human leukocyte antigen (HLA) gene region associates with the risk for several autoimmune diseases, including type 1 diabetes. An association between vitamin D deficiency and several autoimmune diseases has been suggested. We tested the association between serum 25-hydroxyvitamin D (25OHD) concentrations and HLA alleles in pregnant Finnish women. SUBJECTS/METHODS: HLA-B (n=395),...
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