Article
Chemotherapy Effectiveness and Prognosis of Gastric Cancer Influenced by PTPN11 Polymorphisms.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2016
Zhuo Chuanjun, Shao Mingjing, Chen Ce, Lin Chongguang, Jiang Deguo, Chen Guangdong, Tian Hongjun, Wang Lina, Li Jie, Lin Xiaodong
Abstract excerpt
OBJECTIVE: Since gastric cancer (GC) cells exhibited higher grades of SHP-2 encoded by PTPN11 than normal cells, it would be intriguing to explore whether PTPN11 single nucleotide polymorphisms (SNPs) would influence chemotherapy effectiveness and GC prognosis among a Chinese population. METHODS:...
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