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Article

Genome-wide association study on the FEV1/FVC ratio in never-smokers identifies HHIP and FAM13A.

The Journal of allergy and clinical immunology - 1 Feb 2017

van der Plaat Diana A, de Jong Kim, Lahousse Lies, Faiz Alen, Vonk Judith M, van Diemen Cleo C, Nedeljkovic Ivana, Amin Najaf, Brusselle Guy G, Hofman Albert, Brandsma Corry-Anke, Bossé Yohan, Sin Don D, Nickle David C, van Duijn Cornelia M, Postma Dirkje S, Boezen H Marike

Abstract excerpt

BACKGROUND: Although a striking proportion (25% to 45%) of patients with chronic obstructive pulmonary disease are never-smokers, most genetic susceptibility studies have not focused on this group exclusively. OBJECTIVE: The aim of this study was to identify common genetic variants associated with FEV1 and its ratio to forced vital capacity (FVC) in never-smokers. METHODS: Genome-wide association studies were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27612410
DOI: 10.1016/j.jaci.2016.06.062

Genes

HHIP

Provenance

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