Article
Epigenetic studies in Developmental Origins of Health and Disease: pitfalls and key considerations for study design and interpretation.
Journal of developmental origins of health and disease - 1 Feb 2017
Yamada L, Chong S
Abstract excerpt
The field of Developmental Origins of Health and Disease (DOHaD) seeks to understand the relationships between early-life environmental exposures and long-term health and disease. Until recently, the molecular mechanisms underlying these phenomena were poorly understood; however, epigenetics has been proposed to bridge the gap between the environment and phenotype. Epigenetics involves the study of heritable...
Topics
- DNA Methylation
- Environmental Exposure
- Epigenesis, Genetic
- Female
- Human Development
- Humans
- Phenotype
- Pregnancy
- Prenatal Exposure Delayed Effects
