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Article

The developmental origins of health and disease: current theories and epigenetic mechanisms.

Society of Reproduction and Fertility supplement - 1 Jan 2007

Sinclair K D, Lea R G, Rees W D, Young L E

Abstract excerpt

The retrospective cohort studies of David Barker and colleagues during the late 1980s established the principle that the incidence of certain adult diseases such as stroke, type 2 diabetes and dyslipidaemia may be linked to in utero development. Later termed the "Developmental Origins of Health and Disease (DOHaD)" hypothesis, there have been several more recent attempts to explain this phenomenon. Although a...

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Identifiers

PMID: 17491163
DOI: 10.5661/rdr-vi-425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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