Whole exome sequencing analysis reveals TRPV3 as a risk factor for cardioembolic stroke.

doi:10.1160/TH16-02-0113

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Article

Whole exome sequencing analysis reveals TRPV3 as a risk factor for cardioembolic stroke.

Thrombosis and haemostasis - 30 Nov 2016

Carrera Caty, Jiménez-Conde Jordi, Derdak Sophia, Rabionet Kelly, Vives-Bauzá Cristofol, Soriano-Tárrega Carolina, Giralt-Steinhauer Eva, Mola-Caminal Marina, Diaz-Navarro Rosa M, Tur Silvia, Muiño Elena, Gallego-Fabrega Cristina, Beltran Sergi, Roquer Jaume, Ruiz Agustin, Sotolongo-Grau Oscar, Krupinski Jurek, Lee Jin-Moo, Cruchaga Carlos, Delgado Pilar, Malik Rainer, Worrall Brad B, Seshadri Sudha, Montaner Joan, Fernández-Cadenas Israel

Abstract excerpt

Genetic studies suggest that hundreds of genes associated with stroke remain unidentified. Exome sequencing proves useful for finding new genes associated with stroke. We aimed to find new genetic risk factors for cardioembolic stroke by analysing exome sequence data using new strategies. For discovery, we analysed 42 cardioembolic stroke cases and controls with extreme phenotypes (cohort 1), and for replication,...

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Identifiers

PMID: 27604134
DOI: 10.1160/TH16-02-0113

Genes

TRPV3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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