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Article

Whole-exome sequencing of Finnish patients with vascular cognitive impairment.

European journal of human genetics : EJHG - 1 Apr 2021

Mönkäre Saana, Kuuluvainen Liina, Kun-Rodrigues Celia, Carmona Susana, Schleutker Johanna, Bras Jose, Pöyhönen Minna, Guerreiro Rita, Myllykangas Liisa

Abstract excerpt

Cerebral small vessel disease (CSVD) is the most important cause of vascular cognitive impairment (VCI). Most CSVD cases are sporadic but familial monogenic forms of the disorder have also been described. Despite the variants identified, many CSVD cases remain unexplained genetically. We used whole-exome sequencing in an attempt to identify novel gene variants underlying CSVD. A cohort of 35 Finnish patients with...

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Identifiers

PMID: 33268848
DOI: 10.1038/s41431-020-00775-9
PMCID: PMC8115269

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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