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Transcriptional benchmark dose modeling: Exploring how advances in chemical risk assessment may be applied to the radiation field

7 Sept 2016

Abstract excerpt

Recent advances in "-omics" technologies have simplified capacity to concurrently assess expression profiles of thousands of targets in a cellular system. However, compilation and analysis of "omics" data in support of human health protection remains a challenge. Benchmark dose (BMD) modeling is currently being employed in chemical risk assessment to estimate acceptable levels of exposure. Although typically...

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PMID: 27601323
DOI: 10.1002/em.22043

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