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Article

Alterations in BRAF gene, and enhanced mTOR and MAPK signaling in dysembryoplastic neuroepithelial tumors (DNTs).

Epilepsy research - 1 Nov 2016

Kakkar Aanchal, Majumdar Atreye, Kumar Anupam, Tripathi Manjari, Pathak Pankaj, Sharma Mehar C, Suri Vaishali, Tandon Vivek, Chandra Sarat P, Sarkar Chitra

Abstract excerpt

OBJECTIVE: Recently, BRAF V600E mutation, and activation of mTOR and MAPK pathways have been identified in various glial/glioneuronal tumors. Dysembryoplastic neuroepithelial tumors (DNTs) are epilepsy-associated glioneuronal neoplasms which have not been analyzed extensively in this respect. METHODS: Sequencing for BRAF V600E mutation, analysis of BRAF copy number by qRT-PCR, and immunohistochemistry for mTOR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27599148
DOI: 10.1016/j.eplepsyres.2016.08.028

Genes

BRAF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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