Article
Sequence polymorphism in an insect RNA virus field population: A snapshot from a single point in space and time reveals stochastic differences among and within individual hosts.
Virology - 1 Nov 2016
Stenger Drake C, Krugner Rodrigo, Nouri Shahideh, Ferriol Inmaculada, Falk Bryce W, Sisterson Mark S
Abstract excerpt
Population structure of Homalodisca coagulata Virus-1 (HoCV-1) among and within field-collected insects sampled from a single point in space and time was examined. Polymorphism in complete consensus sequences among single-insect isolates was dominated by synonymous substitutions. The mutant spectrum of the C2 helicase region within each single-insect isolate was unique and dominated by nonsynonymous singletons....
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