Article
Complex Sources of Variation in Tissue Expression Data: Analysis of the GTEx Lung Transcriptome.
American journal of human genetics - 1 Sept 2016
McCall Matthew N, Illei Peter B, Halushka Marc K
Abstract excerpt
The sources of gene expression variability in human tissues are thought to be a complex interplay of technical, compositional, and disease-related factors. To better understand these contributions, we investigated expression variability in a relatively homogeneous tissue expression dataset from the Genotype-Tissue Expression (GTEx) resource. In addition to identifying technical sources, such as sequencing date...
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