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Article

Cellular investigations with human antibodies associated with the anti-IgLON5 syndrome.

Journal of neuroinflammation - 1 Sept 2016

Sabater Lidia, Planagumà Jesús, Dalmau Josep, Graus Francesc

Abstract excerpt

BACKGROUND: Antibodies against IgLON5, a neuronal adhesion protein of unknown function, are markers of a novel neurological disorder termed anti-IgLON5 syndrome. The disorder shows a remarkable association with the HLA-DQB1*0501 and HLA-DRB1*1001 alleles, and postmortem studies demonstrate a novel neuronal tauopathy predominantly involving the hypothalamus and tegmentum of the brainstem. The role of IgLON5...

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Source

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Identifiers

PMID: 27586161
DOI: 10.1186/s12974-016-0689-1
PMCID: PMC5007989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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