Article
Prevalence of Quinolone Resistance in Enterobacteriaceae from Sierra Leone and the Detection of qnrB Pseudogenes and Modified LexA Binding Sites.
Antimicrobial agents and chemotherapy - 1 Nov 2016
Leski Tomasz A, Stockelman Michael G, Bangura Umaru, Chae Daniel, Ansumana Rashid, Stenger David A, Vora Gary J, Taitt Chris R
Abstract excerpt
A collection of 74 Enterobacteriaceae isolates found in Bo, Sierra Leone, were tested for quinolone antibiotic susceptibility and resistance mechanisms. The majority of isolates (62%) were resistant to quinolones, and 61% harbored chromosomal gyrA and/or parC mutations. Plasmid-mediated quinolone resistance genes were ubiquitous, with qnrB and aac(6')-Ib-cr being the most prevalent. Mutated LexA binding sites...
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