Article
Single nucleotide polymorphism analysis for the production of valuable steroid intermediates in Mycobacterium neoaurum.
Biotechnology letters - 1 Nov 2016
Liu Min, Zhu Zhan-Tao, Tao Xin-Yi, Wang Feng-Qing, Wei Dong-Zhi
Abstract excerpt
OBJECTIVES: To investigate single nucleotide polymorphism (SNP) in the transformation process of phytosterol to valuable steroid intermediates in three steroid-producing Mycobacterium neoaurum strains using deep sequencing and bioinformation analysis. RESULTS: The assembled contig sequences from RNA sequencing of strains producing 9α-hydroxy-4-androstene-3,17-dione (9OHAD), 1,4-androstadiene-3,17-dione (ADD), and...
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