Article
Tetraspanin CD81 is an adverse prognostic marker in acute myeloid leukemia.
Oncotarget - 20 Sept 2016
Boyer Thomas, Guihard Soizic, Roumier Christophe, Peyrouze Pauline, Gonzales Fanny, Berthon Céline, Quesnel Bruno, Preudhomme Claude, Behal Hélène, Duhamel Alain, Roche-Lestienne Catherine, Cheok Meyling
Abstract excerpt
CD81 is a cell surface protein which belongs to the tetraspanin family. While in multiple myeloma its expression on plasma cells is associated with worse prognosis, this has not yet been explored in acute myeloid leukemia (AML). We measured membrane expression of CD81 on AML cells at diagnosis, evaluated its association with AML characteristics and its influence on patient outcome after intensive chemotherapy in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.