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Article

Polymorphism in ERCC1 confers susceptibility of coronary artery disease and severity of coronary artery atherosclerosis in a Chinese Han population.

Scientific reports - 25 Jul 2017

Zhang Shuai, Wang Xue-Bin, Han Ya-di, Xiong Chen-Ling, Zhou Ye, Wang Chen, Liu Ze-Jin, Yang Na, Zheng Fang

Abstract excerpt

Excision repair cross-complementing 1 (ERCC1) gene encodes ERCC1 protein, which is mainly responsible for the repair of DNA damage in different diseases including coronary artery atherosclerosis by acting as a rate-limiting element in nucleotide excision repair (NER). Using a three-stage case-control study with 3037 coronary artery disease (CAD) patients and 3002 controls, we investigated associations of three...

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Identifiers

PMID: 28743890
DOI: 10.1038/s41598-017-06732-9
PMCID: PMC5526898

Genes

CAD
ERCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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