Article
Assessing Teratogenicity from the Clustering of Abnormal Phenotypes in Individual Zebrafish Larvae.
Zebrafish - 1 Dec 2016
Aalders Jeffrey, Ali Shaukat, de Jong Tom J, Richardson Michael K
Abstract excerpt
In previous publications, we described the population incidence of abnormalities in zebrafish larvae exposed to toxicants. Here, we examine the phenomenon of clustering or co-occurrence of abnormalities in individual larva. Our aim is to see how this clustering can be used to assess the specificity and severity of teratogenic effect. A total of 11,214 surviving larvae, exposed continuously from 1 day...
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