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Article

Immunosuppressive effect of bladder cancer on function of dendritic cells involving of Jak2/STAT3 pathway.

Oncotarget - 27 Sept 2016

Xiu Weigang, Ma Juan, Lei Ting, Zhang Man, Zhou Shangyan

Abstract excerpt

Function of dendritic cells (DCs) is impaired by some cancer cells. However, the effect of bladder cancer cell (BCC) on phenotype and function of DCs remains unclear. In this study, healthy human peripheral blood mononuclear cells (PBMCs) derived DCs were co-cultured with BCC pumc-91 and adriamycin-resistant pumc-91/ADM. The expression of DC markers and costimulatory molecules decreased after co-culture....

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Source

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Identifiers

PMID: 27556503
DOI: 10.18632/oncotarget.11434
PMCID: PMC5325357

Genes

STAT3
ADM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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