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Transcript Levels of Androgen Receptor Variant 7 and Ubiquitin-Conjugating Enzyme 2C in Hormone Sensitive Prostate Cancer and Castration-Resistant Prostate Cancer.

The Prostate - 1 Jan 2017

Lee Chan Ho, Ku Ja Yoon, Ha Jung Min, Bae Sun Sik, Lee Jeong Zoo, Kim Choung-Soo, Ha Hong Koo

Abstract excerpt

PURPOSE: This study is designed to identify the androgen receptor variant 7 (AR-V7) status, clinical significance of AR-V7 in hormone sensitive prostate cancer (HSPC). Then, we evaluated AR-V7 and changes of its target gene, ubiquitin-conjugating enzyme E2C (UBE2C) which is an anaphase-promoting complex/cyclosome (APC/C)-specific ubiquitin-conjugating enzyme, in castration-resistant prostate cancer (CRPC) in...

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PMID: 27550197
DOI: 10.1002/pros.23248

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APC

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