Article
G9a and ZNF644 Physically Associate to Suppress Progenitor Gene Expression during Neurogenesis.
Stem cell reports - 13 Sept 2016
Olsen Jonathan B, Wong Loksum, Deimling Steven, Miles Amanda, Guo Hongbo, Li Yue, Zhang Zhaolei, Greenblatt Jack F, Emili Andrew, Tropepe Vincent
Abstract excerpt
Proliferating progenitor cells undergo changes in competence to give rise to post-mitotic progeny of specialized function. These cell-fate transitions typically involve dynamic regulation of gene expression by histone methyltransferase (HMT) complexes. However, the composition, roles, and regulation of these assemblies in regulating cell-fate decisions in vivo are poorly understood. Using unbiased affinity...
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