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Pharmacologic effects on mitochondrial function

1 Jun 2010

Abstract excerpt

The vast majority of energy necessary for cellular function is produced in mitochondria. Free-radical production and apoptosis are other critical mitochondrial functions. The complex structure, electrochemical properties of the inner mitochondrial membrane (IMM), and genetic control from both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) are some of the unique features that explain why the mitochondria are...

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PMID: 20818734
DOI: 10.1002/ddrr.106

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