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Article

TWIST1 upregulates the MAGEA4 oncogene

17 Aug 2016

Abstract excerpt

Overexpression of MAGEA4 oncogene has been demonstrated in different malignancies; however, little is known about its exact mechanism for overexpression. TWIST1, as a bHLH transcription factor, activates a cell migration-invasion program involved in both embryonic and tumor development. Since MAGEA4 overexpression was statistically correlated to TWIST1, we aimed to elucidate the probable regulatory role of TWIST1...

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PMID: 27533647
DOI: 10.1002/mc.22541

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