Population Genetic Analysis Reveals a High Genetic Diversity in the Brazilian Cryptococcus gattii VGII Population and Shifts the Global Origin from the Amazon Rainforest to the Semi-arid Desert in the Northeast of Brazil.

doi:10.1371/journal.pntd.0004885

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Population Genetic Analysis Reveals a High Genetic Diversity in the Brazilian Cryptococcus gattii VGII Population and Shifts the Global Origin from the Amazon Rainforest to the Semi-arid Desert in the Northeast of Brazil.

PLoS neglected tropical diseases - 1 Aug 2016

Souto Ana C P, Bonfietti Lucas X, Ferreira-Paim Kennio, Trilles Luciana, Martins Marilena, Ribeiro-Alves Marcelo, Pham Cau D, Martins Liline, Dos Santos Wallace, Chang Marilene, Brito-Santos Fabio, Santos Dayane C S, Fortes Silvana, Lockhart Shawn R, Wanke Bodo, Melhem Márcia S C, Lazéra Márcia S, Meyer Wieland

Abstract excerpt

Cryptococcus neoformans and Cryptococcus gattii are responsible globally for almost one million cryptococcosis cases yearly, mostly in immunocompromised patients, such as those living with HIV. Infections due to C. gattii have mainly been described in tropical and subtropical regions, but its adaptation to temperate regions was crucial in the species evolution and highlighted the importance of this pathogenic...

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PMID: 27529479
DOI: 10.1371/journal.pntd.0004885
PMCID: PMC4986980

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