Article
Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts.
mBio - 1 Jan 2011
D'Souza C A, Kronstad J W, Taylor G, Warren R, Yuen M, Hu G, Jung W H, Sham A, Kidd S E, Tangen K, Lee N, Zeilmaker T, Sawkins J, McVicker G, Shah S, Gnerre S, Griggs A, Zeng Q, Bartlett K, Li W, Wang X, Heitman J, Stajich J E, Fraser J A, Meyer W, Carter D, Schein J, Krzywinski M, Kwon-Chung K J, Varma A, Wang J, Brunham R, Fyfe M, Ouellette B F F, Siddiqui A, Marra M, Jones S, Holt R, Birren B W, Galagan J E, Cuomo C A
Abstract excerpt
Cryptococcus gattii recently emerged as the causative agent of cryptococcosis in healthy individuals in western North America, despite previous characterization of the fungus as a pathogen in tropical or subtropical regions. As a foundation to study the genetics of virulence in this pathogen, we sequenced the genomes of a strain (WM276) representing the predominant global molecular type (VGI) and a clinical...
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