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A smooth tubercle bacillus from Ethiopia phylogenetically close to the Mycobacterium tuberculosis complex

18 Nov 2023

Abstract excerpt

The Mycobacterium tuberculosis complex (MTBC) includes several human- and animal-adapted pathogens. It is thought to have originated in East Africa from a recombinogenic Mycobacterium canettii-like ancestral pool. Here, we describe the discovery of a clinical tuberculosis strain isolated in Ethiopia that shares archetypal phenotypic and genomic features of M. canettii strains, but represents a phylogenetic branch...

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PMID: 37980337
DOI: 10.1038/s41467-023-42755-9

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