Article
[Mutations in the Neuraminidase Gene of the Epidemic Influenza Virus Strain Isolated in the 2012-2013 Season and Improvement of a PCR Assay for the Detection of Influenza Virus].
Rinsho byori. The Japanese journal of clinical pathology - 1 Oct 2014
Yanagita Mitsutoshi, Kuwamura Yoshitaka, Kinoshita Satoru, Nakajima Takashi, Tomizawa Syuichi, Ozawa Tetsuo
Abstract excerpt
In 2011, we developed a real-time RT-PCR method to rapidly and sensitively detect three subtypes of influenza A virus [H1N1, H3N2, and influenza (H1N1) 2009] and influenza B virus (the conventional PCR method). This method was useful during the 2011-2012 epidemic season. However, epidemic influenza A virus strain H3N2 in the 2012-2013 season was undetectable by this method, possibly due to mutation in the...
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