Article
Molecular detection of human H7N9 influenza A virus causing outbreaks in China.
Clinical chemistry - 1 Jul 2013
Wong Chloe K S, Zhu Huachen, Li Olive T W, Leung Yin Hung C, Chan Michael C W, Guan Yi, Peiris Joseph S M, Poon Leo L M
Abstract excerpt
BACKGROUND: A novel subtype of influenza A virus (H7N9) was recently identified in humans. The virus is a reassortant of avian viruses, but these human isolates contain mutations [hemagglutinin (HA) Q226L and PB2 E627K] that might make it easier for the virus to adapt to mammalian hosts. Molecular tests for rapid detection of this virus are urgently needed. METHODS: We developed a 1-step quantitative real-time...
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