Article
Venom Insulins of Cone Snails Diversify Rapidly and Track Prey Taxa.
Molecular biology and evolution - 1 Nov 2016
Safavi-Hemami Helena, Lu Aiping, Li Qing, Fedosov Alexander E, Biggs Jason, Showers Corneli Patrice, Seger Jon, Yandell Mark, Olivera Baldomero M
Abstract excerpt
A specialized insulin was recently found in the venom of a fish-hunting cone snail, Conus geographus Here we show that many worm-hunting and snail-hunting cones also express venom insulins, and that this novel gene family has diversified explosively. Cone snails express a highly conserved insulin in their nerve ring; presumably this conventional signaling insulin is finely tuned to the Conus insulin receptor,...
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