Article
Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity.
Molecular & cellular proteomics : MCP - 1 Dec 2013
Jin Ai-hua, Dutertre Sébastien, Kaas Quentin, Lavergne Vincent, Kubala Petra, Lewis Richard J, Alewood Paul F
Abstract excerpt
Marine cone snails have developed sophisticated chemical strategies to capture prey and defend themselves against predators. Among the vast array of bioactive molecules in their venom, peptide components called conotoxins or conopeptides dominate, with many binding with high affinity and selectivity to a broad range of cellular targets, including receptors and transporters of the nervous system. Whereas the...
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