Article
The genetic basis of the comorbidity between cannabis use and major depression.
Addiction (Abingdon, England) - 1 Jan 2017
Hodgson Karen, Almasy Laura, Knowles Emma E M, Kent Jack W, Curran Joanne E, Dyer Thomas D, Göring Harald H H, Olvera Rene L, Woolsey Mary D, Duggirala Ravi, Fox Peter T, Blangero John, Glahn David C
Abstract excerpt
BACKGROUND AND AIMS: While the prevalence of major depression is elevated among cannabis users, the role of genetics in this pattern of comorbidity is not clear. This study aimed to estimate the heritability of cannabis use and major depression, quantify the genetic overlap between these two traits and localize regions of the genome that segregate in families with cannabis use and major depression. DESIGN:...
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