Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A route to new cancer therapies: the FA pathway is essential in BRCA1- or BRCA2-deficient cells.

Nature structural & molecular biology - 3 Aug 2016

Lachaud Christophe, Rouse John

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein
Share to Breast Neoplasms
Share to Fanconi Anemia Complementation Group D2 Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Mutant Proteins

Share to Mutation

Share to Ovarian Neoplasms

Source

Identifiers

PMID: 27487393
DOI: 10.1038/nsmb.3276

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A route to new cancer therapies: the FA pathway is essential in BRCA1- or BRCA2-deficient cells.PMID 27487393Read ↗

DNA repair: exploiting the Fanconi anemia pathway as a potential therapeutic target.Semantic proximity Read ↗

DNA Damage Repair Deficiency and Synthetic Lethality for Cancer Treatment.Semantic proximity Read ↗

The Yin and Yang of treating BRCA-deficient tumors.Semantic proximity Read ↗

BRCA1 RING Function Is Essential for Tumor Suppression but Dispensable for Therapy ResistanceSemantic proximity Read ↗

Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?Semantic proximity Read ↗

[Roles of BRCA1 and BRCA2 in DNA repair and tumor suppression].Semantic proximity Read ↗

Drug Insight: cancer therapy strategies based on restoration of endogenous cell death mechanismsSemantic proximity Read ↗

Natural Small Molecules in Breast Cancer Treatment: Understandings from a Therapeutic ViewpointSemantic proximity Read ↗

Synthetic lethality: exploiting the addiction of cancer to DNA repair.Semantic proximity Read ↗

Emerging functions of the Fanconi anemia pathway at a glance.Semantic proximity Read ↗

Targeting Fanconi anemia/BRCA2 pathway defects in cancer: the significance of preclinical pharmacogenomic models.Semantic proximity Read ↗

The Fanconi anaemia/BRCA pathway and cancer susceptibility. Searching for new therapeutic targets.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.