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Article

Quantitative assessment of the spatial heterogeneity of tumor-infiltrating lymphocytes in breast cancer.

Breast cancer research : BCR - 29 Jul 2016

Mani Nikita L, Schalper Kurt A, Hatzis Christos, Saglam Ozlen, Tavassoli Fattaneh, Butler Meghan, Chagpar Anees B, Pusztai Lajos, Rimm David L

Abstract excerpt

BACKGROUND: Tumor-infiltrating lymphocyte (TIL) count in breast cancer carries prognostic information and represents a potential predictive marker for emerging immunotherapies. However, the distribution of the lymphocyte subpopulations is not well defined. The goals of this study were to examine intratumor heterogeneity in TIL subpopulation counts in different fields of view (FOV) within each section, in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27473061
DOI: 10.1186/s13058-016-0737-x
PMCID: PMC4966732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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